The Ultimate Collection combines everything into one Big Box. The Second Edition Base Game of sacrifice, betrayal and hoarding. Four Souls+ adds more characters, monsters, and loot to make the game even more replayable. And Requiem the vast expansion that almost doubles the number of cards in the game. All in one place The Binding of Isaac: Four Souls Requiem is a vast expansion that almost doubles the number of cards in the game. It features 269 new cards that you can add to the copy of Binding of Isaac: Four Souls you already own (1st or 2nd edition). The new features make the game even more complex and exciting Defeat every monster, find every treasure and loot every room in this: the pinnacle of the Binding of Isaac: Four Souls product line. The Ultimate Collection is just that, Ultimate. It contains everything from the base game, the Four Souls+ and Requiem expansions, as well as deluxe, upgraded dice and token components. All of this is packaged in a glorious new gold collectors box that is sure to take pride of place on players game shelves.